Tuesday, 24 March 2015

Deep Brain Stimulation May Ease Some Parkinson's Pain for Years

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But new aches develop for many, researchers report


WebMD News from HealthDay

By Steven Reinberg

HealthDay Reporter

MONDAY, March 23, 2015 (HealthDay News) -- People with Parkinson's disease who undergo deep brain stimulation may experience long-term pain relief, a small, new study from Korea suggests.

However, three-quarters of the patients developed new pain in muscles and joints eight years after the procedure was performed, the researchers found.

"It is potentially important that some pain types improved, but also important to understand why other types of pain did not benefit from stimulation," said Dr. Michael Okun, national medical director for the National Parkinson Foundation.

Deep brain stimulation involves surgically implanting a battery pack called a neurostimulator in the brain. This sends out tiny electrical pulses to targeted areas of the brain, to block signals that cause the tremors and other motor symptoms of Parkinson's, according to the foundation.

While this and other advances have helped ease movement problems associated with the disorder, less has been done to understand the debilitating pain associated with Parkinson's, experts say.

"This study draws attention to an important and often neglected area of Parkinson disease care and research," Okun said.

Typically, pre-existing pain and its response to deep brain stimulation therapy is not measured, he explained.

Pain that starts after the implantation surgery also needs to be studied, Okun added, noting it is likely related to the disease itself and other medical conditions.

This latest study was published online March 23 in the journal JAMA Neurology.

A team led by Dr. Beom Jeon, from the Seoul National University Hospital, studied the long-term effects of deep brain stimulation on pain in 24 Parkinson patients. The researchers measured patients' pain before surgery and eight years later.

Sixteen of the patients experienced pain before surgery when not taking medication. Their average pain score was 6.2 on a scale of 1 to 10 where 10 represents the most pain, the researchers reported.

Jeon's team found that the pain suffered before surgery had improved or disappeared eight years later.

But 18 patients developed new pain during the follow-up period.

New pain affected 47 body parts, with an average pain score of 4.4. For more than half of these patients, the new pain was described as aching and cramping in joints or muscles, the researchers said.



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