Saturday, 31 January 2015

Some With Kidney Stones Might Have Calcium Buildup in Blood Vessels: Study

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These patients might need closer monitoring for further signs of pending heart trouble, researcher says


WebMD News from HealthDay

By Rosemary Black

HealthDay Reporter

FRIDAY, Jan. 30, 2015 (HealthDay News) -- Some people who develop recurring kidney stones may also have high levels of calcium deposits in their blood vessels, and that could explain their increased risk for heart disease, new research suggests.

"It's becoming clear that having kidney stones is a bit like having raised blood pressure, raised blood lipids [such as cholesterol] or diabetes in that it is another indicator of, or risk factor for, cardiovascular disease and its consequences," said study co-author Dr. Robert Unwin, of University College London. Unwin is currently chief scientist with the AstraZeneca cardiovascular & metabolic diseases innovative medicines and early development science unit, in Molndal, Sweden.

The main message, Unwin said, "is to begin to take having kidney stones seriously in relation to cardiovascular disease risk, and to practice preventive monitoring and treatments, including diet and lifestyle."

Some 10 percent of men and 7 percent of women develop kidney stones at some point in their lives, and research has shown that many of these people are at heightened risk for high blood pressure, chronic kidney disease and heart disease, the researchers said.

But study author Dr. Linda Shavit, a senior nephrologist at Shaare Zedek Medical Center in Jerusalem, and her colleagues wanted to find out whether the heart issues that can occur in some of those with kidney stones might be caused by high levels of calcium deposits in their blood vessels.

Using CT scans, they looked at calcium deposits in the abdominal aorta, one of the largest blood vessels in the body. Of the 111 people in the study, 57 suffered recurring kidney stones that were comprised of calcium (kidney stones can be made up of other minerals, depending on the patient's circumstances, the researchers noted), and 54 did not have kidney stones.

Not only did the investigators find that those with recurring kidney stones made of calcium have higher calcium deposits in their abdominal aortas, but they also had less dense bones than those who did not have kidney stones.

Earlier research has shown that calcium buildup in blood vessels frequently goes hand in hand with bone loss, which suggests a link between osteoporosis and atherosclerosis, or hardening of the arteries.



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