Wednesday, 29 January 2014

Hearing Loss Tied to Faster Brain Shrinkage With Age

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Follow-up studies needed to show whether treating hearing problems could delay mental decline, experts say


WebMD News from HealthDay

Study found seniors who struggled with hearing

By Amy Norton

HealthDay Reporter

TUESDAY, Jan. 28, 2014 (HealthDay News) -- Older adults with impaired hearing may have a faster rate of brain shrinkage as they age, a new study suggests.

A number of studies have found that older people with hearing loss tend to have a quicker decline in their memory and thinking skills, compared to those with normal hearing.

"We've known that common, age-related hearing loss is associated with cognitive [mental] decline. The question is, why?" said Dr. Frank Lin, an assistant professor at Johns Hopkins University in Baltimore, and the lead researcher on the new study.

The findings, he said, offer one potential explanation: Older adults with hearing problems lose brain volume more quickly than their peers with normal hearing.

The precise reason is not clear, and the real-life impact is unknown. The study did not test participants' actual mental ability.

But the "biggest question," Lin said, is whether treating hearing impairment can slow changes in brain structure and, more importantly, delay dementia.

He and his colleagues are now planning a trial to test that idea.

The current findings are based on 126 adults aged 56 to 86 who underwent yearly MRI scans to track brain-tissue changes for up to a decade. At the time of the first scan, they also had a physical and a hearing test. Of participants, 51 showed some degree of hearing loss -- mostly the mild variety where people have trouble hearing soft voices, for instance.

Lin's team found that older adults with hearing problems showed a faster decline in brain volume over the years -- especially in brain regions involved in processing sound and speech.

The study, published online Jan. 9 in the journal NeuroImage, cannot prove that hearing loss directly causes brain-tissue loss. But the basic "use it or lose it" principle may apply, according to Lin.

"The ear is no longer sending clear messages to the brain," he said. Without that input, sound-processing brain regions may change in structure.

What's more, Lin said, those brain areas have other jobs, too. Among other things, they play a role in memory and processing information other than sounds.

A hearing expert not involved in the study said it's "interesting," and raises the question of whether treating hearing impairment can prevent brain-tissue loss or slow mental decline.

"But we need a study to test that, and that study has yet to be done," said Dr. Ian Storper, an otologist at Lenox Hill Hospital, in New York City.

Even though researchers have found a link between hearing loss and mental decline, Storper noted, "that doesn't prove causation." Both hearing loss and brain-volume loss are common parts of aging, and there are many other variables that may be related to both, Storper added.



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