Friday 13 February 2015

Some Stroke Survivors May Face Heightened Cancer Risk, Study Shows

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But cancer only affected about 2 percent of those in two-year follow-up period


WebMD News from HealthDay

By Amy Norton

HealthDay Reporter

THURSDAY, Feb. 12, 2015 (HealthDay News) -- Older adults who survive a stroke may have a higher-than-average risk of developing cancer in the next few years, a new study suggests.

Researchers followed nearly 3,700 ischemic stroke survivors who were started out cancer-free. Over two years follow-up, 2 percent were newly diagnosed with cancer. The researchers determined their risk of a cancer diagnosis was 40 percent higher than the norm for older U.S. adults.

Experts said it's not clear why the risk was elevated. That's likely because the study wasn't designed to discover a cause. It was only designed to look for a link between these conditions. But the association may have something to do with risk factors that underlie both stroke and certain cancers, such as smoking or unhealthy eating habits.

Another potential culprit is chronic, low-grade inflammation -- which is believed to contribute to both heart trouble and cancer, said Dr. Philip Gorelick, a stroke specialist at Mercy Health and Michigan State University in Grand Rapids, who was not involved in the study.

But while the "why" is not yet certain, the findings add to evidence of a link between stroke and cancer, according to Gorelick.

"In practice, we do see people with [undiagnosed] cancer first present with a stroke," Gorelick explained. Often, that's related to tumors of the colon or pancreas. The cancers can cause a blood clot in the arteries supplying the brain -- which then triggers an ischemic stroke, the most common form of stroke, he said.

Lead researcher Dr. Malik Adil, of the Zeenat Qureshi Stroke Institute in St. Cloud, Minn., said in fact it's possible that some of the survivors in the current study had cancer that was present before the stroke, but not recognized.

Still, both Adil and Gorelick stressed that stroke survivors should not panic. The vast majority of study patients did not develop cancer during the two-year follow-up.

"The cancer risk was increased relative to the general population, but it was not a high risk," Gorelick said.

Adil was scheduled to present the findings Thursday at the American Stroke Association's annual meeting in Nashville. Studies reported at medical meetings are usually considered preliminary until the findings are published in a peer-reviewed journal.



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